DEPARTMENT OF PATHOLOGY GRADUATE PROGRAM IN PATHOBIOLOGY

Program overview

The Department of Pathology Graduate Program in Pathobiology is designed to provide students with the training necessary to study the cellular and molecular mechanisms of disease. This program is one of the multidisciplinary programs in Medical Sciences Program, Faculty of Medicine, Khon Kaen University . A strength of our program is the active participation of both basic and clinical researchers that provides insight and exposure to the clinical aspect of biomedical research through the Liver Fluke and Cholangiocarcinoma Research Center of Khon Kaen University. The program is dedicated to the development of each student as an independent biomedical research scientist. The doctoral dissertation is planned and conducted with the close consultation of the student's mentor and thesis advisory committee. The dissertation is an original contribution into the field of cellular and molecular pathology. The required course curriculum can be completed during the first two years while making a substantial start toward a research project. It is expected that all requirements for the PhD can be completed within 5 years.

Required Course Work

A minimum of 48 credits for students who have master degree and 72 credits for those who start with graduated bachelor degree must be taken for the whole curriculum. All students must complete core and required courses, excluding seminar courses, prior to registering for the Qualifying Examination (QE). Proposal defense examination must be accomplished within 4 semesters after starting dissertation enrolment. A minimum cumulative grade point average of 3.00 is required for completion of the PhD program.

Details of the credits needed in each student category are shown as follow:

A. Students who have master degree.

B. Students who have bachelor degree.

Core Courses

In addition to the requirements from the Medical Sciences Program,
the Pathobiology PhD Program requires the following courses:

Dissertations

Electives

Students can choose any other courses in the pool of Medical Science Program (more than 60 courses available) that fit particular interest of their dissertation project.

356 712 Cells and Molecular Biology 3 (3-0-6)
The molecular organization of cells and cellular energy , metabolism, genome, gene regulation, chemical components of cells, structure and function of cells, cell growth and division, cell communication , cell development and differentiation , cell interactions, cell pathology and cell death, molecular and cellular basis of diseases, tumor development, the evolution of cell and the immune system.

356 713 Laboratory Techniques in Medical Sciences 2 (0-6-3)
Principle and laboratory techniques in medical sciences including research ethics, basic techniques in biochemistry, molecular biology, microbiology, immunology, parasitology, pathology, anatomy, physiology and /or pharmacology

356 714 Medical Science Research Methodology 3 (2-3-5)
Principles, research design and methodology in medical science research, practical and appropriate biostatistical analysis in medical sciences, including various presentations of research outcome

356 991 Seminar in Medical Sciences I 1 (1-0-2)
Review of recent researches in medical sciences from experiments and /or reports and international publications, practice presentation with clear, precise and critical exposition, including reliable and precise answers to audience's questions

356 992 Seminar in Medical Sciences II 1 (1-0-2)
Review of recent researches in medical sciences from experiments and /or reports and international publications, related to scope of thesis proposal, practice presentation with clear, precise and critical exposition, including reliable and precise answers to audience's questions

356 993 Seminar in Medical Sciences III 1 (1-0-2)
Presentation of the progress report of the thesis, discus the result related to the other published papers, practice presentation with clear, precise and critical exposition, including reliable and precise answers to audience's questions

365 711 Principle of Pathology 2 (2-0-2)
Pathologic principles of human diseases. Emphasis on the causes and mechanisms of disease processes, gross and microscopic features of diseases, and their functional alterations. General pathologic processes including cell injury, inflammation and repair, immunologic disorders, hemodynamic disturbances, neoplasia, nutritional and genetic disorders.

365 716 General Pathology Laboratory 1 (0-3-1.5)
General pathology laboratory practice in gross and microscopic levels including cell injury, inflammation and repair, infection, hemodynamic disturbances and neoplasia.

365 717 Systemic Pathology 2 (2-0-4)
Systemic pathology including blood and lymphoid, gastrointestinal, hepatobiliary, respiratory, cardiovascular, genitourinary and nervous systems.

365 718 Systemic Pathology Laboratory 1 (0-3-1.5)
Systemic pathology laboratory practice in gross and microscopic levels of diseases of blood and lymphoid system, gastrointestinal system, hepatobiliary system, respiratory system, cardiovascular system, genitourinary system and nervous system.

365 720 Principle of Cytopathology 2 (2-0-4)
Cytology and cytopathology of gynecologic system and non-gynecologic system such as respiratory system, urinary system, and gastrointestinal system both in normal and disease conditions. The diseases including inflammation, tumor, precancerous and cancerous lesion, and effects of chemotherapy or radiotherapy. Cytopathology of fine needle aspiration from tumor or various lesions in the body.

365 721 Oncology 2 (2-0-4)
Basic concepts of cancer biology highlighting chemical carcinogenesis, the genetics of cancer development and the biochemistry of neoplasia. The mechanisms by which environmental factors-including exposure to radiation, chemicals, viruses, and endogenous factors such as genes, hormones, and the immune system-affect tumor development. Overview the molecular mechanisms of gene controlling tumor growth and spreading to other tissue. Morphological, biochemical and physiological properties of tumor cells. Clinical oncology and theoretical basis of chemotherapy. Cancer epidemiology.

365 722 Advanced Cancer Biology 2 (2-0-4)
Current knowledge in the molecular basis of cancer development, progression and metastasis. Cell cycle and its regulation; modulation of cell death and apoptosis, signal transduction pathway controlling cell growth and differentiation; tumor suppressor genes and genetic susceptibility to cancer; mechanisms of carcinogenesis, DNA repair and fixation of mutations. Cancer biology, angiogenesis and metastasis. Factors involve in direct invasion, vascular and lymphatic invasion.

365 723 Cytogenetics and Molecular Cytogenetics 2 (2-0-4)
Molecular aspect of human chromosome related to genetic diseases and cancers. Included are basic knowledge of human chromosomes and their molecular structure, cytogenetic nomenclature, and various forms of chromosomal abnormalities. Chromosomal landmark for disease loci mapping and the identification of diseased genes. Cytogenetics and molecular genetics of certain genetic diseases and cancers are also discussed.

365 997 Dissertation 48 credits
Conducting advanced scientific research, writing the research results in the form of thesis with the ability to initiate and effectively conduct research in order to identify problems and find solutions to the problems in medical, public health and related areas. In add ition, at least 1 paper on the research study must be published or accepted in an internationally recognized journal.

365 998 Dissertation 48 credits
Conducting advanced scientific research, writing the research results in the form of thesis with the ability to initiate and effectively conduct research in order to identify problems and find solutions to the problems in medical, public health and related areas. In add ition, at least 1 paper on the research study must be published or accepted in an internationally recognized journal.

365 999 Dissertation 36 credits
Conducting advanced scientific research, writing the research results in the form of thesis with the ability to initiate and effectively conduct research in order to identify problems and find solutions to the problems in medical, public health and related areas. In add ition, at least 1 paper on the research study must be published or accepted in an internationally recognized journal.